Histopathological Effects of Pesticide Imidacloprid Insecticide on the Liver in Male Rabbits

Excessive use of pesticides has led to increasing concern about undesirable effects on human health and the environment. Imidacloprid is an internationally used neonicotinoid insecticide due its significant toxicity insects. Its residues may reach food chain, which important for examining potentially harmful properties imidacloprid exposure. The current study aimed characterize histopathological liver male rabbits.
 administration daily at two chronic oral doses (45 mg/kg 90 mg/kg, daily) 37 days. Treated rabbits groups treatment concentrations revealed many changes in liver, such as congestion blood vessels, hemorrhage, inflammation, ballooned hepatocytes, steatosis, infiltration, vasodilatation, necrosis fibrosis. results established that was significantly worse specific organs digestive system (liver) rabbits.